Anti-eIF4EBP1 Antibody [JJ09-25]

HUABIO

Anti-eIF4EBP1 Antibody [JJ09-25]

7

ImmunoFluorescence, ImmunoPrecipitation, Western Blot, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin

WB,IF-Cell,IF-Tissue,IHC-P,IP,FC

Research Use Only

Monoclonal

JJ09-25

1 mg/ml

Unconjugated

EIF4EBP1

eukaryotic translation initiation factor 4E binding protein 1

4E-BP1, 4EBP1, BP-1, PHAS-I, eukaryotic translation initiation factor 4E-binding protein 1, eIF4E-binding protein 1, phosphorylated heat- and acid-stable protein regulated by insulin 1

Rabbit

IgG

Eukaryotic translation initiation factor 4E-binding protein 1

This gene encodes one member of a family of translation repressor proteins. The protein directly interacts with eukaryotic translation initiation factor 4E (eIF4E), which is a limiting component of the multisubunit complex that recruits 40S ribosomal subunits to the 5 end of mRNAs. Interaction of this protein with eIF4E inhibits complex assembly and represses translation. This protein is phosphorylated in response to various signals including UV irradiation and insulin signaling, resulting in its dissociation from eIF4E and activation of cap-dependent mRNA translation.

Human, Mouse, Rat

Human,Mouse,Rat

-20°C,2°C to 8°C

41116161