Anti-ELK1 Antibody [SU32-05]

HUABIO

Anti-ELK1 Antibody [SU32-05]

7

ImmunoFluorescence, ImmunoPrecipitation, Western Blot, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin

WB,IF-Cell,IHC-P,IP

Research Use Only

Monoclonal

SU32-05

1 mg/ml

Unconjugated

ELK1

ETS transcription factor ELK1

ETS domain-containing protein Elk-1, ELK1, ETS transcription factor, ELK1, member of ETS oncogene family, ETS-like gene 1, tyrosine kinase (ELK1) oncogene

Rabbit

IgG

ETS domain-containing protein Elk-1

ETS Like-1 protein Elk-1 is a protein that in humans is encoded by the ELK1. Elk-1 functions as a transcription activator. It is classified as a ternary complex factor (TCF), a subclass of the ETS family, which is characterized by a common protein domain that regulates DNA binding to target sequences. Elk1 plays important roles in various contexts, including long-term memory formation, drug addiction, Alzheimers disease, Down syndrome, breast cancer, and depression. Given its role as a transcription factor, Elk1 is expressed in the nuclei of non-neuronal cells. The protein is present in the cytoplasm as well as in the nucleus of mature neurons. In post-mitotic neurons, a variant of Elk1, sElk1, is expressed solely in the nucleus because it lacks the NES site present in the full-length protein. Moreover, while Elk1 is broadly expressed, actual levels vary among tissues. The rat brain, for example, is extremely rich in Elk1, but the protein is exclusively expressed in neurons.

Human, Mouse, Rat

Human,Mouse,Rat

-20°C,2°C to 8°C

41116161