Anti-Envelope glycoprotein H; Envelope glycoprotein L [Fab-RC], Human IgG1, Fc Silent(tm), kappa

Absolute Antibody

Anti-Envelope glycoprotein H; Envelope glycoprotein L [Fab-RC], Human IgG1, Fc Silent(tm), kappa

9

This antibody is specific for the combination of gH and gL and does not detect the proteins in isolation.

The original antibody was used for surface plasmon resonance on VZV gHgL. This antibody was used for a neutralization assay. Here is showed it was able to inhibit gB/gHgL-mediated membrane fusion. The structure of this antibody was determined using x-ray crystallography (Xing et al., 2015; PMID:25918416). This antibody was used for immunohistochemistry on fixed and unfixed VZV-infected and control HFL cells. This antibody was also used for a plaque reduction assay on VZV-infected HFL cells. Further this antibody was used for immunoprecipitation on VZV-infected and uninfected HFL cells (Birlea et al., 2013; PMID:23077312).

ImmunoPrecipitation, ImmunoHistoChemistry, Neutralisation/Blocking, Other Application

Research Use Only

Monoclonal

Fab-RC

Human

IgG1

This is a reformatted human IgG1 Fc Silent™ antibody, based on the original human IgG format, created for improved compatibility with existing reagents, assays and techniques.

Virus

-20°C,2°C to 8°C

12352203