Anti-EpCAM Mouse mAb

PTM BIO

Anti-EpCAM Mouse mAb

5

Flow Cytometry

FC

Research Use Only

Monoclonal

10610

Unconjugated

Mouse

IgG

Epithelial cell adhesion molecule

Epithelial cell adhesion molecule (EpCAM) is a transmembrane glycoprotein mediating Ca2+-independent homotypic cell–cell adhesion in epithelia. EpCAM is also involved in cell signaling, migration, proliferation, and differentiation. Additionally, it has oncogenic potential via its capacity to upregulate c-Myc, E-FABP, and Cyclins A & E. Since EpCAM is expressed exclusively in epithelia and epithelial-derived neoplasms, it can be used as diagnostic marker for various cancers. It appears to play a role in tumorigenesis and metastasis of carcinomas, so it can also act as a potential prognostic marker and as a potential target for immunotherapeutic strategies.

Stable for 12 months from date of receipt/reconstitution.

Human

Human

Protein G purified

Store at -20°C. Avoid freeze/thaw cycles.

12352203