Anti-EpCAM [MT201 (Adecatumumab; HD69)]

Absolute Antibody

Anti-EpCAM [MT201 (Adecatumumab; HD69)]

7

Immunohistochemistry was performed on human metastatic breast cancer tissue using this antibody (Schmidt et al, 2010; pmid:19633042). ELISA was performed on recombinant EpCAM protein using this antibody (Raum et al, 2000; pmid:11419181). Flow cytometry using this antibody was done on cells (Raum et al, 2000; pmid:11419181). Western blot was performed on 119 polypeptides of 13 amino acids shifted by two amino acids covering the entire extracellular domain of EpCAM. This antibody was used (Raum et al, 2000; pmid:11419181). Surface plasmon resonance was performed on the EpCAM protein using this antibody (Raum et al, 2000; pmid:11419181). This antibody was used for flow cytometery on KATO III cells (Naundorf et al, 2002; pmid:12115595). A cytotoxicity experiment was performed on PMBC using this antibody (Naundorf et al, 2002; pmid:12115595). Phase II trials were performed on prostate cancer patients (Marschner et al, 2010; pmid:20606402). Phase I trials were performed on prostate cancer patients (Oberneder et al, 2006; pmid:16930989).

Flow Cytometry, Western Blot, ELISA, ImmunoHistoChemistry

therapeutic; ELISA; FC; IHC; WB

Research Use Only

Monoclonal

MT201 (Adecatumumab; HD69)

EPCAM

epithelial cell adhesion molecule

adenocarcinoma-associated antigen; cell surface glycoprotein Trop-1; DIAR5; EGP-2; EGP314; EGP40; epithelial cell adhesion molecule; epithelial glycoprotein 314; ESA; HNPCC8; human epithelial glycoprotein-2; KS1/4; KSA; M4S1; major gastrointestinal tumor-associated protein GA733-2; membrane component, chromosome 4, surface marker (35kD glycoprotein); MIC18; MK-1; TACSTD1; TROP1; trophoblast cell surface antigen 1; tumor-associated calcium signal transducer 1

Mouse

IgG2b

Epithelial cell adhesion molecule

This chimeric mouse antibody was made using the variable domain sequences of the original Human IgG1 format, for improved compatibility with existing reagents, assays and techniques.

Human

The original antibody was generated by panning against a naturally expressed human library.

-20°C,2°C to 8°C

12352203