Anti-eRF3a/GSPT1 Rabbit mAb

PTM BIO

Anti-eRF3a/GSPT1 Rabbit mAb

5

Western Blot

WB

Research Use Only

Monoclonal

JRMR-10481-47

Unconjugated

Rabbit

IgG

Eukaryotic peptide chain release factor GTP-binding subunit ERF3A

Involved in translation termination in response to the termination codons UAA, UAG and UGA. Stimulates the activity of ETF1. Involved in regulation of mammalian cell growth. Component of the transient SURF complex which recruits UPF1 to stalled ribosomes in the context of nonsense-mediated decay (NMD) of mRNAs containing premature stop codons. Required for SHFL-mediated translation termination which inhibits programmed ribosomal frameshifting (-1PRF) of mRNA from viruses and cellular genes.

Stable for 12 months from date of receipt/reconstitution.

Human, Monkey, Mouse, Rat

Human, Mouse, Rat, Monkey

Protein A purified

Store at -20°C. Avoid freeze/thaw cycles.

12352203