Anti-ERK5 Antibody [SD2084]
ET1612-7
ApplicationsFlow Cytometry, ImmunoFluorescence, ImmunoPrecipitation, Western Blot
Product group Antibodies
ReactivityHuman, Mouse
TargetMAPK7
Overview
- SupplierHUABIO
- Product NameAnti-ERK5 Antibody [SD2084]
- Delivery Days Customer7
- ApplicationsFlow Cytometry, ImmunoFluorescence, ImmunoPrecipitation, Western Blot
- Applications SupplierWB,IF-Cell,IF-Tissue,IP,FC
- CertificationResearch Use Only
- ClonalityMonoclonal
- Clone IDSD2084
- Concentration1 mg/ml
- ConjugateUnconjugated
- Gene ID5598
- Target nameMAPK7
- Target descriptionmitogen-activated protein kinase 7
- Target synonymsBMK1, ERK4, ERK5, PRKM7, mitogen-activated protein kinase 7, BMK-1, BMK1 kinase, ERK-5, MAP kinase 7, MAPK 7, big MAP kinase 1, extracellular-signal-regulated kinase 5
- HostRabbit
- IsotypeIgG
- Protein IDP0C865
- Protein NameMitogen-activated protein kinase 7
- Scientific DescriptionThe activation of signal transduction pathways by growth factors, hormones and neurotransmitters is mediated through two closely related MAP kinases, p44 and p42, designated extracellular-signal related kinase 1 (ERK 1) and ERK 2, respectively. ERK proteins are regulated by dual phosphorylation at specific tyrosine and threonine sites mapping within a characteristic Thr-Glu-Tyr motif. Phosphorylation at both the Thr and Tyr residues is required for full enzymatic activation. In response to activation, MAP kinases phosphorylate downstream components on serine and threonine. Upstream MAP kinase regulators include MAP kinase kinase (MEK), MEK kinase and Raf-1. The ERK family has three additional members: ERK 3, ERK 5 and ERK 6.
- ReactivityHuman, Mouse
- Reactivity SupplierHuman,Mouse
- Reactivity Supplier NoteRat
- Storage Instruction-20°C,2°C to 8°C
- UNSPSC41116161