Anti-Estradiol [D12]

Absolute Antibody

Anti-Estradiol [D12]

9

This antibody is specific for estradiol. Estradiol is an estrogen steroid hormone and the major female sex hormone. It is involved in the regulation of the estrous and menstrual female reproductive cycles.

The scFv version of this antibody binds estradiol with an affinity of 3.7nM in and ELISA. To assess its physical characteristics the binding affinity of this antibody was also measured using SPR on estradiol using the scFv version of this antibody (Vaughan et al, 1996; pmid:9630891). To test the binding of this antibody, an ELISA was performed on either thyroglobulinoestradiol, BSA-oestriol or BSA using the scFv version of this antibody. Further the rate of association and dissociation was determined using surface plasmon resonance. This was performed with estradiol as antigen and the scFv version of this antibody (Pope et al, 1996; pmid:9373313).

ELISA, Other Application

Research Use Only

Monoclonal

D12

Human

IgG1

This full-length, reformatted human antibody was made using the variable domain sequences of the original Human scFv format, for improved compatibility with existing reagents, assays and techniques.

Other Species

-20°C,2°C to 8°C

12352203