Anti-Estrogen Related Receptor alpha Antibody [SC57-07]

HUABIO

Anti-Estrogen Related Receptor alpha Antibody [SC57-07]

7

Flow Cytometry, ImmunoFluorescence, ImmunoPrecipitation, Western Blot, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin

WB,IP,FC,IHC-P

Research Use Only

Monoclonal

SC57-07

1 mg/ml

Unconjugated

ESRRA

estrogen related receptor alpha

ERR1, ERRa, ERRalpha, ESRL1, NR3B1, steroid hormone receptor ERR1, ERR-alpha, estrogen receptor-like 1, estrogen-related nuclear receptor alpha, nuclear receptor subfamily 3 group B member 1

Rabbit

IgG

Steroid hormone receptor ERR1

Estrogen related receptor alpha (ERRalpha) is a nuclear receptor in the superfamily of ligand-regulated transcription factors and is a member of the NR3B orphan nuclear receptor subgroup (consisting of alpha, beta and gamma). ERRalpha plays a role in modulating the estrogen signaling pathway. In addition, the expression of ERRalpha has been shown to increase during fasting and cold exposure. ERRalpha may be important for regulating mitochondrial biogenesis and oxidative metabolism by acting directly on genes necessary for mitochondrial function. Mice lacking ERRalpha are unable to maintain their body temperature in the cold. ERRalpha may also be involved in the maintenance and formation of cartilage. This information could be useful in finding therapeutic agents for a variety of diseases affecting the joints.

Human, Mouse

Human,Mouse

Rat

-20°C,2°C to 8°C

41116161