Anti-Factor VII [RFF-VII/1]

Absolute Antibody

Anti-Factor VII [RFF-VII/1]

9

This antibody is specific for human coagulation factor VII, a serine protease that initiates the extrinsic pathway of coagulation and circulates as a zymogen.

This antibody binds with high affinity to human factor VII, and acts as an inhibitor of factor VII coagulation activity (Takase et al, 1988).When coupled to sepharose, this antibody has been used to deplete factor VII from plasma (Sarial et al, 2012). The specificity of this antibody for factor VII has been confirmed in a double monoclonal immunoradiometric assay for factor VII antigen (Takase et al, 1988).

Neutralisation/Blocking, RadioImmunoAssay

Research Use Only

Monoclonal

RFF-VII/1

F7

coagulation factor VII

coagulation factor VII; coagulation factor VII (serum prothrombin conversion accelerator); eptacog alfa; FVII coagulation protein; proconvertin; SPCA

Human

IgG1

Coagulation factor VII

This chimeric human antibody was made using the variable domain sequences of the original Mouse IgG1 format, for improved compatibility with existing reagents, assays and techniques.

Human

-20°C,2°C to 8°C

12352203