Anti-FADD Antibody

HUABIO

Anti-FADD Antibody

7

Western Blot

WB,FC

Research Use Only

Polyclonal

1 mg/ml

Unconjugated

Fadd

Fas associated via death domain

Mort1/FADD, FAS-associated death domain protein, FAS-associating death domain-containing protein, Fas (TNFRSF6)-associated via death domain, Fas-associating protein with death domain, mediator of receptor induced toxicity, protein FADD

Rabbit

IgG

FAS-associated death domain protein

The Fas-associated death domain-containing protein (FADD) was initially identified as an adaptor required for cell death signal transduction initiated by Fas. FADD contains two protein-protein interaction structures: the death domain (DD) at the carboxy terminus and the death effector domain (DED) at the amino terminus. FADD is involved in signaling induced by other DRs such as TNFR-I, TRAIL receptors (or DR4/5), and DR3. Overexpression of FADD causes apoptosis, which can be blocked by the cow pox protein CrmA, suggesting that FADD lies upstream of ICE and possibly other serine proteases.

Mouse

-20°C,2°C to 8°C

41116161