Anti-Fatty Acid Synthase Antibody [JJ0939]

HUABIO

Anti-Fatty Acid Synthase Antibody [JJ0939]

7

Flow Cytometry, ImmunoFluorescence, ImmunoPrecipitation, Western Blot, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin

WB,IF-Cell,IF-Tissue,IHC-P,IP,FC

Research Use Only

Monoclonal

JJ0939

1 mg/ml

Unconjugated

FASN

fatty acid synthase

FAS, OA-519, SDR27X1, fatty acid synthase, 3-hydroxyacyl-[acyl-carrier-protein] dehydratase, 3-oxoacyl-[acyl-carrier-protein] reductase, 3-oxoacyl-[acyl-carrier-protein] synthase, Acyl-[acyl-carrier-protein] hydrolase, Enoyl-[acyl-carrier-protein] reductase, [Acyl-carrier-protein] S-acetyltransferase, [Acyl-carrier-protein] S-malonyltransferase, short chain dehydrogenase/reductase family 27X, member 1, type I fatty acid synthase

Rabbit

IgG

Fatty acid synthase

Fatty acid biosynthesis is mediated by seven catalytic enzymes and an acyl carrier protein (ACP), to which various acyl intermediates are covalently attached. Fatty Acid Synthase (FAS) is the anabolic enzyme that contains the seven unique catalytic sites and mediates the conversion of acetyl-CoA and malonyl-CoA, in the presence of the cofactor NADPH, into long-chain saturated fatty acids, such as palmitate. Human Fatty Acid Synthase cDNA encodes a 2,504 amino acid protein. Catalytically active Fatty Acid Synthase is a homodimer. Human Fatty Acid Synthase mRNA is variably expressed with abundant levels present in brain, lung and liver. Fatty acid synthetic metabolism is abnormally elevated in tumor cells and may support cell growth or survival of malignant cancers.

Human, Mouse, Rat

Human,Mouse,Rat

-20°C,2°C to 8°C

41116161