Anti-FDFT1 Antibody [JE60-69]

HUABIO

Anti-FDFT1 Antibody [JE60-69]

2

ImmunoFluorescence, Western Blot, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin

Research Use Only

Monoclonal

JE60-69

1 mg/ml

Unconjugated

FDFT1

farnesyl-diphosphate farnesyltransferase 1

DGPT, ERG9, SQS, SQSD, SS, squalene synthase, FPP:FPP farnesyltransferase, presqualene-di-diphosphate synthase, squalene synthetase

Rabbit

IgG

Squalene synthase

Several proteins mediate the biosynthesis of cholesterol. The first specific step in the cholesterol biosynthetic pathway is the conversion of transfarnesyl-diphosphate to Squalene, which is catalyzed by the endoplasmic reticulum membrane-associated enzyme Squalene synthetase, also designated Squalene synthase and Farnesyl-diphosphate farnesyltransferase. Squalene synthetase is located at a branch point in the mevalonate pathway and is also involved in isoprenoid biosynthesis. Squalene epoxidase, also designated Squalene monooxygenase, is a multi-pass microsomal membrane-associated enzyme that catalyzes the first oxygenation step in sterol biosynthesis and most likely functions as one of the rate-limiting enzymes in this pathway. Squalene epoxidase may form a complex with Squalene synthetase.

-20°C,2°C to 8°C

41116161