Anti-Ferritin [AMB8LK]

Absolute Antibody

Anti-Ferritin [AMB8LK]

9

This antibody was capable of immunoprecipitating ferritin (PMID: 6817879). The original antibody binds human ferritin with a binding affinity of Kd= 5.1nM (EP2193147). The thiolated version of this antibody was conjugated to maleimide-activated polylactide nanoparticles (NPs) to generate immunonanoparticles, which may carry drugs to desired overexpressing antigen cells potentially leading to improved drug therapy and reduced systemic adverse effects (PMID: 19835957). Preclinical studies showed that the immunoconjugate with 90Y has 98% stability over 7 days. A very good pancreatic adenocarcinoma tumor targeting was observed especially with the Bz-DTPA-AMB8LK (PMID: 17383579)

ImmunoPrecipitation, Other Application

Research Use Only

Monoclonal

AMB8LK

FTMT

ferritin mitochondrial

MTF, ferritin, mitochondrial, ferritin H subunit, mitochondrial ferritin

Mouse

IgG1

Ferritin, mitochondrial

Human

-20°C,2°C to 8°C

12352203