Anti-FGFR1 Oncogene Partner Antibody [JE64-24]
HA721047
ApplicationsFlow Cytometry, ImmunoFluorescence, Western Blot, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
Product group Antibodies
TargetCEP43
Overview
- SupplierHUABIO
- Product NameAnti-FGFR1 Oncogene Partner Antibody [JE64-24]
- Delivery Days Customer2
- ApplicationsFlow Cytometry, ImmunoFluorescence, Western Blot, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
- CertificationResearch Use Only
- ClonalityMonoclonal
- Clone IDJE64-24
- Concentration1 mg/ml
- ConjugateUnconjugated
- Gene ID11116
- Target nameCEP43
- Target descriptioncentrosomal protein 43
- Target synonymsFGFR1OP, FOP, centrosomal protein 43, FGFR1 oncogene partner, fibroblast growth factor receptor 1 oncogene partner
- HostRabbit
- IsotypeIgG
- Protein IDO95684
- Protein NameCentrosomal protein 43
- Scientific DescriptionFOP, also known as FGFR1OP (FGFR1 oncogene partner), is a 399 amino acid protein that localizes to the centrosome and contains one LisH domain. Expressed ubiquitously with highest expression in kidney, heart, muscle, colon, liver, testis and pancreas, FOP functions as a homodimer that interacts with EB1 and CEP350 and is essential for anchoring microtubules to centrosomes. Chromosomal aberrations that involve the FOP gene are associated with the pathogenesis of stem cell myeloproliferative disorder (MPD), a condition that is characterized by eosinophilia and myeloid hyperplasia and ultimately leads to acute myeloid leukemia. FOP is expressed as multiple isoforms that are produced by alternative splicing events.
- Storage Instruction-20°C,2°C to 8°C
- UNSPSC41116161