Anti-Fluorescein [4-4-20 (enhanced)]

Absolute Antibody

Anti-Fluorescein [4-4-20 (enhanced)]

7

This antibody, a humanized, enhanced scFv of the original mouse IgG2a antibody, was constructed by grafting the CDRs of the original antibody onto the humanized 4D5 anti-HER2 antibody framework, and subsequently enhancing it with respect to folding and stability via randomization in the form of DNA shuffling, as well as oligonucleotides encoding mutations at defined positions (Jung et al., 1999; PMID: 10556036). The original antibody was tested against FlI-BSA. The enhanced antibody fragment was tested against FITC-BSA. This antibody can be used as an isotype control in both in vitro and in vivo applications. This antibody is not conjugated to fluorescein.

Other Application

Research Use Only

This is a bispecific, knob-into-hole heterodimerized antibody, with one arm directed against fluorescein (Fab) and one arm directed against mouse CD3e (scFv).

-20°C,2°C to 8°C

12352203