Anti-FNTB Antibody [SC06-44]

HUABIO

Anti-FNTB Antibody [SC06-44]

7

Western Blot

WB,IF-Cell,IF-Tissue

Research Use Only

Monoclonal

SC06-44

1 mg/ml

Unconjugated

FNTB

farnesyltransferase, CAAX box, subunit beta

FPTB, protein farnesyltransferase subunit beta, CAAX farnesyltransferase subunit beta, FTase-beta, epididymis secretory sperm binding protein, farnesyltransferase, CAAX box, beta, ras proteins prenyltransferase subunit beta

Rabbit

IgG

Protein farnesyltransferase subunit beta

Mammalian protein farnesyl transferases are heterodimeric proteins containing two nonidentical alpha and beta subunits that attach farnesyl residues to a cysteine at the fourth position from the COOH terminus of several proteins, including nuclear lamins and p21Ras proteins. The natural substrates contain the Cys-A-A-Xaa recognition sequence, where the A residues are aliphatic and Xaa represents methionine, serine, glutamine or cysteine. The purified farnesyl transferase is an a-b heterodimer. The beta subunit, which is known as FTbeta, CAAX farnesyltransferase subunit beta, or Ras proteins prenyltransferase subunit beta, is a 437 amino acid protein that contains five PFTB repeats and binds the peptide substrate. The alpha subunit is suspected to participate in formation of a stable complex with the substrate farnesyl pyrophosphate.

Human

Human

Rat

-20°C,2°C to 8°C

41116161