Anti-FosB Antibody [SN703]

HUABIO

Anti-FosB Antibody [SN703]

7

ImmunoFluorescence, Western Blot, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin

WB,IHC-P,IP

Research Use Only

Monoclonal

SN703

1 mg/ml

Unconjugated

FOSB

FosB proto-oncogene, AP-1 transcription factor subunit

AP-1, G0S3, GOS3, GOSB, protein FosB, FBJ murine osteosarcoma viral oncogene homolog B, FosB proto-oncogene, AP-1 trancription factor subunit, G0/G1 switch regulatory protein 3, activator protein 1, transcription factor AP-1 subunit FosB

Rabbit

IgG

Protein FosB

The v-Fos oncogene was initially identified as the transforming gene of two independent murine osteosarcoma virus isolates and an avian nephroblastoma virus. The cellular homolog, c-Fos, encodes a nuclear phosphoprotein that is rapidly and transiently induced by a variety of agents and functions as a transcriptional regulator for several genes. In contrast to c-Jun proteins, which form homo- and heterodimers which bind to specific DNA TPA response elements (TREs), c-Fos proteins are only active as heterodimers with members of the Jun gene family. Murine Fos B encodes a nuclear protein of 338 amino acids which has 70% homology with c-Fos, exhibits similar kinetics of expression as c-Fos and forms heterodimers with both c-Jun and Jun B which bind to TRE DNA response elements. Functional homologs of c-Fos and Fos B include Fra-1 and Fra-2 genes.

Human, Mouse

Human,Mouse

Rat

-20°C,2°C to 8°C

41116161