anti-GABAB Receptor 1 antibody [S93A-49]

Arigo Biolaboratories

anti-GABAB Receptor 1 antibody [S93A-49]

23

ImmunoFluorescence, Western Blot, ImmunoCytoChemistry

Research Use Only

Monoclonal

S93A-49

1 mg/ml

Unconjugated

Gabbr1

gamma-aminobutyric acid type B receptor subunit 1

GABA-B receptor 1; GABABR1; GABA-BR1; GABA-B-R1; gamma-aminobutyric acid (GABA) B receptor 1; gamma-aminobutyric acid type B receptor subunit 1; gb1

Mouse

IgG1

Gamma-aminobutyric acid (GABA) is the main inhibitory neurotransmitter in the mammalian central nervous system. GABA exerts its effects through ionotropic [GABA(A/C)] receptors, to produce fast synaptic inhibition, and metabotropic [GABA(B)] receptors, to produce slow, prolonged inhibitory signals. The GABA(B) receptor consists of a heterodimer of two related 7-transmembrane receptors, GABA(B) receptor 1 and GABA(B) receptor 2. The GABA(B) receptor 1 gene is mapped to chromosome 6p21.3 within the HLA class I region close to the HLA-F gene. Susceptibility loci for multiple sclerosis, epilepsy, and schizophrenia have also been mapped in this region. Alternative splicing of this gene generates multiple transcript variants. [provided by RefSeq, Jun 2009]

Rat

-20°C

12352203