Anti-Galectin 3 Antibody [JF39-10]

HUABIO

Anti-Galectin 3 Antibody [JF39-10]

7

Flow Cytometry, ImmunoFluorescence, Western Blot, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin

WB,IF-Cell,IF-Tissue,FC,IHC-P

Research Use Only

Monoclonal

JF39-10

1 mg/ml

Unconjugated

LGALS3

galectin 3

CBP35, GAL3, GALBP, GALIG, L31, LGALS2, MAC2, galectin-3, 35 kDa lectin, IgE-binding protein, MAC-2 antigen, advanced glycation end-product receptor 3, carbohydrate-binding protein 35, epididymis secretory sperm binding protein, galactose-specific lectin 3, laminin-binding protein, lectin L-29, lectin, galactoside-binding, soluble, 3

Rabbit

IgG

Galectin-3

Galectins are a family of soluble b-galactoside-binding animal lectins that modulate cell-to-cell adhesion and cell-to-extracellular matrix (ECM) inter- actions and play a role in tumor progression, pre-mRNA splicing and apop-tosis. The galectin-3 protein, also known as Mac-2, hMac-2, GALBP, CBP35 or LGALS3, contains a single carbohydrate binding domain, which binds galactose-containing glycoconjugates. Galectin-3 is expressed in colonic and intestinal epithelium, inflammatory macrophages, papillary and follicular carcinomas, neoplastic astrocytes and some B and T lymphocytes. Upregulated expression of galectin-3 is involved in cancer progression and metastasis. Galectin-3 mediates the endocytosis of beta1 Integrins in a lactose-dependent manner and is associated with thyroid malignancy and Crohns disease. It may also be used as a marker for diagnosing cases involving Hurthle cell adenomas and carcinomas.

Human, Mouse

Human,Mouse

Rat

-20°C,2°C to 8°C

41116161