Anti-gamma Catenin Antibody [JF0973]

HUABIO

Anti-gamma Catenin Antibody [JF0973]

7

Flow Cytometry, ImmunoFluorescence, Western Blot, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin

WB,IF-Cell,IF-Tissue,IHC-P,FC

Research Use Only

Monoclonal

JF0973

1 mg/ml

Unconjugated

JUP

junction plakoglobin

CTNNG, DP3, DPIII, PDGB, PG, PKGB, junction plakoglobin, catenin (cadherin-associated protein), gamma 80kDa, desmoplakin III, desmoplakin-3, desmosomal protein 3

Rabbit

IgG

Junction plakoglobin

The catenins, alpha, beta and gamma, are proteins which bind to the highly conserved, intracellular cytoplasmic tail of E-cadherin. Together, the catenin/cadherin complexes play an important role mediating cellular adhesion. alpha-catenin was initially described as an E-cadherin associated protein, and since has been shown to associate with other members of the cadherin family, such as N-cadherin and P-cadherin. beta-catenin associates with the cytoplasmic portion of E-cadherin, which is necessary for the function of E-cadherin as an adhesion molecule. beta-catenin has also been found in complexes with the tumor suppressor protein APC. gamma-catenin, also known as plakoglobin, binds with alpha-catenin and N-cadherin. It has been shown that the transmembrane phosphatase PTP? associates with catenin/cadherin complexes and may regulate complex signaling.

Human, Mouse

Human,Mouse

Rat

-20°C,2°C to 8°C

41116161