Anti-gamma Sarcoglycan Antibody [JA11-57]

HUABIO

Anti-gamma Sarcoglycan Antibody [JA11-57]

7

ImmunoPrecipitation, Western Blot, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin

WB,IP,IHC-P

Research Use Only

Monoclonal

JA11-57

1 mg/ml

Unconjugated

SGCG

sarcoglycan gamma

35DAG, A4, DAGA4, DMDA, DMDA1, LGMD2C, LGMDR5, MAM, SCARMD2, gamma-SG, gamma-sarcoglycan, 35 kDa dystrophin-associated glycoprotein, 35kD dystrophin-associated glycoprotein, sarcoglycan, gamma (35kDa dystrophin-associated glycoprotein)

Rabbit

IgG

Gamma-sarcoglycan

The sarcoglycan transmembrane proteins are members of the dystrophin complex. Sarcoglycans cluster together to form a complex, which is localized in the cell membrane of skeletal, cardiac and smooth muscle fibers. Four sarcoglycan subunit proteins, designated alpha-, beta-, gamma- and delta-sarcoglycan, form a complex on the skeletal muscle cell surface membrane. A genetic defect in any one of these proteins causes the loss or marked decrease of the whole sarcoglycan complex, which is observed in the autosomal recessive muscular dystrophy, sarcoglycanopathy. In smooth muscle, beta- and delta-sarcoglycans are associated with epsilon-sarcoglycan, a glycoprotein homologous to alpha-sarcoglycan. Additionally, a complete deficiency in delta-sarcoglycan is the cause of the Syrian hamster BIO.14 cardiomyopathy.

Human

Human

Mouse

-20°C,2°C to 8°C

41116161