Anti-GATA2 Mouse mAb

PTM BIO

Anti-GATA2 Mouse mAb

5

Western Blot

WB

Research Use Only

Monoclonal

JMMR-2706

Unconjugated

Mouse

IgG

Endothelial transcription factor GATA-2

GATA2 or GATA-binding factor 2 is a transcription factor, i.e. a nuclear protein which regulates the expression of genes. It regulates many genes that are critical for the embryonic development, self-renewal, maintenance, and functionality of blood-forming, lympathic system-forming, and other tissue-forming stem cells. GATA2 is a transcriptional activator which regulates endothelin-1 gene expression in endothelial cells. It binds to the consensus sequence 5'-AGATAG-3'. GATA2 is encoded by the GATA2 gene, a gene which often suffers germline and somatic mutations which lead to a wide range of familial and sporadic diseases, respectively.

Stable for 12 months from date of receipt/reconstitution.

Human, Mouse

Human, Mouse

Protein A purified

Store at -20°C. Avoid freeze/thaw cycles.

12352203