Anti-Genome polyprotein [MA28-7], Mouse IgG1, kappa

Absolute Antibody

Anti-Genome polyprotein [MA28-7], Mouse IgG1, kappa

9

This antibody is specific for binds specifically to the 5-fold vertex encompassing VP1-98E and VP1-244K.

The original version of this antibody was used for a neutralization assay by preincubating the EV71 (Human enterovirus 71) virus with the antibody and then adding Vero cells. This antibody neutralized only EV71 strains B4, B3 and C2. The structure of the fab version of this antibody was determined using cryo-EM (Lee et al., 2013; PMID:23946455). This antibody was used to immunoprecipitate EV-A71-1095 capsids from solution (Nishimura et al., 2015; PMID:26430888).

ImmunoPrecipitation, Neutralisation/Blocking, Other Application

Research Use Only

Monoclonal

MA28-7

Mouse

IgG1

Genome polyprotein

Virus

-20°C,2°C to 8°C

12352203