Anti-gHgL [CL40]

Absolute Antibody

Anti-gHgL [CL40]

7

The antibody blocks EBV-mediated membrane fusion with both B cells and epithelial cells and it retains its inhibitory activity as a monomeric Fab. Flow cytometry cell counts showed that Fab fragment inhibits virus entry. Neutralization experiments with epithelial cells using an EBV-GFP reporter virus and purified Fab were performed. Fluorescence images obtained at 24 h postinfection and flow cytometry cell counts showed that the Fab inhibits virus entry. Fab inhibition of cell-cell fusion and EBV infection exhibited similar concentration dependence. (PMID: 28939750) The cell-surface expression of gHgL was evaluated using the antibody by CELISA. (PMID: 27929061)

Flow Cytometry, Western Blot, ELISA, Neutralisation/Blocking

FC; neutralizing; WB; ELISA

Research Use Only

Monoclonal

CL40

BKRF2

envelope glycoprotein L

HHV4_BKRF2, envelope glycoprotein L

Mouse

IgG1

Envelope glycoprotein L

Virus

Epstein-Barr virus

-20°C,2°C to 8°C

12352203