Anti-Ghrelin [5A1]

Absolute Antibody

Anti-Ghrelin [5A1]

9

The kinetic constant of the humanized, affinity matured Fab version of the antibody was measured by KinExA (Kd= 1 pM). The binding affinity of the Fab fragment to Ghrelin was measured by surface plasmon resonance (Kd= 2 pM). Rats were injected with human ghrelin and their food consumption was measured. Results showed that if the humanized Fab version of the antibody was administrated, their food consumption was effectively reduced (US7479271).

Other Application

Research Use Only

Monoclonal

5A1

GHRL

ghrelin and obestatin prepropeptide

appetite-regulating hormone; ghrelin, growth hormone secretagogue receptor ligand; ghrelin/obestatin preprohormone; ghrelin/obestatin prepropeptide; growth hormone-releasing peptide; In2c-preproghrelin; motilin-related peptide; MTLRP; prepro-appetite regulatory hormone; preproghrelin

Mouse

IgG1

Appetite-regulating hormone

-20°C,2°C to 8°C

12352203