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ProductsBack/Anti-GITR [YGITR765]

Anti-GITR [YGITR765]

Ab00631-23.0
Absolute Antibody
ApplicationsFlow Cytometry, Neutralisation/Blocking
Product group Antibodies
ReactivityMouse
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Overview

  • Supplier
    Absolute Antibody
  • Product Name
    Anti-GITR [YGITR765]
  • Delivery Days Customer
    7
  • Antibody Specificity
    This antibody binds murine GITR.
  • Application Supplier Note
    A chimeric version of this antibody featuring a human IgG1 Fc-portion engineered to lack the N-linked glycosylation site at amino acid 297 was shown to enhance humoral immune responses by blocking GITR signallin (Ponte 2010).
  • Applications
    Flow Cytometry, Neutralisation/Blocking
  • Applications Supplier
    FC; block
  • Certification
    Research Use Only
  • Clonality
    Monoclonal
  • Clone ID
    YGITR765
  • Host
    Rabbit
  • Isotype
    IgG
  • Scientific Description
    This chimeric rabbit antibody was made using the variable domain sequences of the original Rat IgG2b format, for improved compatibility with existing reagents, assays and techniques.
  • Reactivity
    Mouse
  • Reactivity Supplier
    Mouse
  • Reactivity Supplier Note
    nB2/6TG cells transfected with mouse GITR injected into DA rats.
  • Storage Instruction
    -20°C,2°C to 8°C
  • UNSPSC
    12352203