Anti-Glutamate receptor 1 Antibody [SD2010]

HUABIO

Anti-Glutamate receptor 1 Antibody [SD2010]

7

Western Blot, ImmunoHistoChemistry, ImmunoHistoChemistry Frozen, ImmunoHistoChemistry Paraffin

WB,IHC-P,IP

Research Use Only

Monoclonal

SD2010

1 mg/ml

Unconjugated

GRIA1

glutamate ionotropic receptor AMPA type subunit 1

GLUH1, GLUR1, GLURA, GluA1, HBGR1, MRD67, MRT76, glutamate receptor 1, AMPA 1, AMPA receptor subunit GluA1, AMPA-selective glutamate receptor 1, gluR-1, gluR-A, gluR-K1, glutamate receptor, ionotropic, AMPA 1

Rabbit

IgG

Glutamate receptor 1

Glutamate receptors mediate most excitatory neurotransmission in the brain and play an important role in neural plasticity, neural development and neurodegeneration. Ionotropic glutamate receptors are categorized into NMDA receptors and kainate/AMPA receptors, both of which contain glutamate-gated, cation-specific ion channels. Kainate/AMPA receptors are co-localized with NMDA receptors in many synapses and consist of seven structurally related subunits designated GluR-1 to -7. The kainate/AMPA receptors are primarily responsible for the fast excitatory neuro-transmission by glutamate whereas the NMDA receptors are functionally characterized by a slow kinetic and a high permeability for Ca2+ ions. The NMDA receptors consist of five subunits: epsilion 1, 2, 3, 4 and one zeta subunit. The zeta subunit is expressed throughout the brainstem whereas the four epsilon subunits display limited distribution.

Mouse, Rat

Mouse,Rat

Human

-20°C,2°C to 8°C

41116161