Anti-gp120 [u5.5]

Absolute Antibody

Anti-gp120 [u5.5]

9

Has been tested against the primary field isolates of Japanese hemophiliacs seropositive for HIV-1 and protect SCID-hu mice from infection from these isolates. u5.5 was used as a humanized antibody and found to have a high neutralization activity. As of such it has been proposed as a protective antibody, however its epitope specificity gives it a limited range (Okamoto et al, 1998). It has been used in Western Blots to detect the V3 epitope of HIV-1 (Honda et al, 1995).

Western Blot, ELISA, Neutralisation/Blocking

Research Use Only

Monoclonal

u5.5

Mouse

IgG1

Envelope glycoprotein gp160

Virus

-20°C,2°C to 8°C

41116161