Anti-GP25-200 [4H9]

Absolute Antibody

Anti-GP25-200 [4H9]

7

This antibody binds the GP25-200 antigen of Cryptosporidium parvum. Cryptosporidium parvum is a coccidian parasite that infects intestinal epithelium and causes diarrheal disease in humans and other agriculturally important food animals for which specific

This antibody can be used for the identification of sporozoites and GP25-200 antigen of C. parvum using western blot. The identification of sporozoite-neutralizing antibody was done using ELISA (PMID: 10768951). This antibody in combination with PLA2 or LL37 was also used in the generation of a biocide fusion proteins to kill C. parvum sporozoites in vitro and in vivo (PMID: 20086143).

Western Blot, ELISA

WB; ELISA; therapeutic

Research Use Only

Monoclonal

4H9

Rabbit

IgG

This chimeric rabbit antibody was made using the variable domain sequences of the original Mouse IgG1 format for improved compatibility with existing reagents assays and techniques.

Parasite

Cryptosporidium parvum

The original antibody was generated by immunizing female BALB/c mice intraperitoneally and subcutaneously with purified P23 emulsified in monophosphoryl A-trehalose dimycolate adjuvant.

-20°C,2°C to 8°C

12352203