Anti-GRAMD1A Antibody [1-E4]

HUABIO

Anti-GRAMD1A Antibody [1-E4]

7

ImmunoFluorescence, Western Blot, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin

WB,IF-Cell,IHC-P

Research Use Only

Monoclonal

1-E4

2 mg/ml

Unconjugated

GRAMD1A

GRAM domain containing 1A

KIAA1533, protein Aster-A, Aster-A, GRAM domain-containing protein 1A

Mouse

IgM

Protein Aster-A

GRAMD1A first finds in human embryonic stem cell, and expresses in ectoderm, mesoderm and endoderm tissues and many tumor cells, its function hasnt been explored. The researh has determined the role of GRAM1DA in the self-renewal of HCC stem cell and resistance to chemotherapy by overexpressing GRAMD1A, and the role of GRAMD1A in tumor growth by overexpressing or downregulating GRAMD1A. GRAMD1A is a prognostic factor for HCC, it promoted the self-renewal of HCC stem cell, resistance to chemotherapy and tumor growth through promoting STAT5, Inhibition of STAT5 in indicated cells with GRAMD1A overexpression inhibited the self-renewal of HCC stem cell, resistance to chemotherapy and tumor growth.

Human, Mouse

Human,Mouse

-20°C,2°C to 8°C

41116161