Anti-GXM [2E9]

Absolute Antibody

Anti-GXM [2E9]

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This antibody is specific for GXM or glucuronoxylomannan from Cryptococcus neoformans. GXM is a polysaccharide expressed on the surface of C. neoformans. This antibody binds an epitope of C. neoformans that is different from the epitope of another anti-GX

This antibody was used for the immunofluorescent labelling of C. neoformans serotype D and A. This antibody can be used in combination with another anti-GXM antibody 2H1 for detection of all four serotypes of C. neoformans GXM using sandwich ELISA. The antibody 2H1 is used as capture antibody and 2E9 is used as a detection antibody (PMID: 7622223).

ImmunoFluorescence, ELISA

ELISA; IF

Research Use Only

Monoclonal

2E9

Rabbit

IgG

This chimeric rabbit antibody was made using the variable domain sequences of the original Human IgM format for improved compatibility with existing reagents assays and techniques.

Fungus

Cryptococcus neoformans

The original antibody was generated from the peripheral blood lymphocytes of glucuronoxylomannan-tetanus toxoid conjugate (GXM-TT)-immunized individual.

-20°C,2°C to 8°C

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