Anti-GXM [2H1]

Absolute Antibody

Anti-GXM [2H1]

9

This antibody is specific for GXM from C.neoformans. GXM is a polysacharide experssed on the surface of c.neoformans.

To characterize the mouse version of this antibody an ELISA was performed on native and de-O-acetylated serotype A GMX using the mouse version of this antibody (Casadevall et al, 1992; pmid:1583327). In research on the efficacy of the mouse version of this antibody against diverse strains of Cryptococcus neoformans. This antibody showed the ability to reduce the amount of yeast cells present in the organs of mice (Mukherjee et al, 1995; pmid:7642262).

ELISA

Research Use Only

Monoclonal

2H1

Rabbit

IgG

This chimeric rabbit antibody was made using the variable domain sequences of the original Mouse IgG1 format, for improved compatibility with existing reagents, assays and techniques.

Fungus

-20°C,2°C to 8°C

12352203