Anti-HBeAg [E6]

Absolute Antibody

Anti-HBeAg [E6]

7

This antibody defines the e-antigen determinant HBe-beta, and is specific for unassembled dimers. Two copies of the antibody are able to bind captured HBeAg dimers, indicating two accessible epitopes per dimer. E6 binding is inhibited by other members of

This Fab forms a stable complex with the recombinantly-expressed HBeAg dimer. Consequently, this antibody can be used to facilitate the crystallization of the complex, and the establishment of its structure (DiMattia, 2013).

Other Application, RadioImmunoAssay

Mab: RIA; cross-competition assay; serum protein electrophoresis. Fab; crystallization

Research Use Only

Monoclonal

E6

Mouse

IgG1

This reformatted mouse antibody was made using the variable domain sequences of the original Mouse IgG format, for improved compatibility with existing reagents, assays and techniques.

Virus

Hep B

This antibody was produced by immunizing BALB/c and SJL/Olac mice with HBeAg derived by denaturing human liver HBcAg. The subsequent production of the Fab is not detailled.

-20°C,2°C to 8°C

12352203