Anti-HCV core protein [19D9D6]

Absolute Antibody

Anti-HCV core protein [19D9D6]

9

This antibody is specific for the protein sequence QIVGGVYLL located at residues 29-37 of the HCV core protein. Hepatitis C virus (HCV) is the primary cause of hepatitis transmitted through blood transfusion. It is an enveloped virus that contains a singl

This antibody was used for an indirect ELISA to detect anti-HCV core response in human sera, an ELISA competition assays to assess the interaction between monoclonal antibodies and anticore human sera, a sandwich ELISA for the capture and detection of viral core antigen in chronic HCV patient sera, and a sandwich ELISA for the detection of recombinant core protein (Jolivet-Reynaud et al., 1998; PMID: 9829633). The crystal structure of the Fab version of this antibody was solved in complex with an HCV core protein-derived peptide (residues 13-40), revealing the hydrophobic nature of the recognized epitope (Menez et al., 2003; PMID: 12574359).

ELISA

Research Use Only

Monoclonal

19D9D6

Mouse

IgG1

Virus

-20°C,2°C to 8°C

12352203