Anti-Hemoglobin subunit alpha Antibody [PD00-16]

HUABIO

Anti-Hemoglobin subunit alpha Antibody [PD00-16]

2

Western Blot, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin

Research Use Only

Monoclonal

PD00-16

1 mg/ml

Unconjugated

HBA1

hemoglobin subunit alpha 1

ECYT7, HBA-T3, HBH, METHBA, hemoglobin subunit alpha, alpha globin chain, alpha one globin, alpha-2 globin chain, delta globin, hemoglobin alpha 1 globin chain, hemoglobin, alpha 1

Rabbit

IgG

Hemoglobin subunit alpha

The human alpha globin gene cluster located on chromosome 16 spans about 30 kb and includes seven loci: 5- zeta - pseudozeta - mu - pseudoalpha-1 - alpha-2 - alpha-1 - theta - 3. The alpha-2 (HBA2) and alpha-1 (HBA1) coding sequences are identical. These genes differ slightly over the 5 untranslated regions and the introns, but they differ significantly over the 3 untranslated regions. Two alpha chains plus two beta chains constitute HbA, which in normal adult life comprises about 97% of the total hemoglobin; alpha chains combine with delta chains to constitute HbA-2, which with HbF (fetal hemoglobin) makes up the remaining 3% of adult hemoglobin. Alpha thalassemias result from deletions of each of the alpha genes as well as deletions of both HBA2 and HBA1; some nondeletion alpha thalassemias have also been reported.

-20°C,2°C to 8°C

41116161