Anti-hINSR [IR 47-46]

Absolute Antibody

Anti-hINSR [IR 47-46]

7

This antibody has been used in immunoprecipitation assays with radiolabelled human insulin receptor (hINSR) (Soos et al, 1986). It has also been used in immunoblot analysis with purified hINSR (Soos et al, 1986), revealing that it binds to the receptors alpha subunit. This antibody has been shown to cause >80% inhibition of insulin binding to IM-9 cells (Soos et al, 1986), and to block receptor activation.

ImmunoPrecipitation, Western Blot, Neutralisation/Blocking

IP; IB; blocking

Research Use Only

Monoclonal

IR 47-46

INSR

insulin receptor

CD220; HHF5; insulin receptor; IR

Mouse

IgG1

Insulin receptor

Human, bovine

This antibody was raised by immunising BALB/c mice with IM-9 lymphocytes, and boosting with purified human placental insulin receptor prior to fusion.

-20°C,2°C to 8°C

12352203