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Insulin Receptor beta antibody

GTX101136
GeneTex
ApplicationsImmunoFluorescence, Western Blot, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
DownloadDatasheet
Product group Antibodies
TargetINSR
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Overview

  • Supplier
    GeneTex
  • Product Name
    Insulin Receptor antibody
  • Delivery Days Customer
    9
  • Application Supplier Note
    WB: 1:500-1:3000. IHC-P: 1:100-1:1000. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
  • Applications
    ImmunoFluorescence, Western Blot, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
  • Certification
    Research Use Only
  • Clonality
    Polyclonal
  • Concentration
    1.31 mg/ml
  • Conjugate
    Unconjugated
  • Gene ID3643
  • Target name
    INSR
  • Target description
    insulin receptor
  • Target synonyms
    CD220; HHF5; insulin receptor; IR
  • Host
    Rabbit
  • Isotype
    IgG
  • Protein IDP06213
  • Protein Name
    Insulin receptor
  • Scientific Description
    After removal of the precursor signal peptide, the insulin receptor precursor is post-translationally cleaved into two chains (alpha and beta) that are covalently linked. Binding of insulin to the insulin receptor (INSR) stimulates glucose uptake. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq]
  • Storage Instruction
    -20°C or -80°C,2°C to 8°C
  • UNSPSC
    12352203

References

  • An inducible model of chronic hyperglycemia.
    Read more
  • Oral administration of nano-tyrosol reversed the diabetes-induced liver damage in streptozotocin-induced diabetic rats.
    Read more
  • Radix Rehmanniae Praeparata (Shu Dihuang) exerts neuroprotective effects on ICV-STZ-induced Alzheimers disease mice through modulation of INSR/IRS-1/AKT/GSK-3beta signaling pathway and intestinal microbiota.
    Read more
  • Activation of AT2 receptors prevents diabetic complications in female db/db mice by NO-mediated mechanisms. Dominici FP et al., 2020 Oct, Br J Pharmacol
    Read more
  • Regulation of chitosan-mediated differentiation of human olfactory receptor neurons by insulin-like growth factor binding protein-2. Huang TW et al., 2019 Oct 1, Acta Biomater
    Read more
  • 3,3-Diindolylmethane Enhances Glucose Uptake Through Activation of Insulin Signaling in 3T3-L1 Adipocytes. Choi KM et al., 2018 Jul, Obesity (Silver Spring)
    Read more
  • PTPRD silencing by DNA hypermethylation decreases insulin receptor signaling and leads to type 2 diabetes. Chen YT et al., 2015 May 30, Oncotarget
    Read more

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