Insulin Receptor beta antibody
GTX101136
ApplicationsImmunoFluorescence, Western Blot, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
Product group Antibodies
ReactivityHuman, Mouse, Rat, Zebra Fish
TargetINSR
Overview
- SupplierGeneTex
- Product NameInsulin Receptor antibody
- Delivery Days Customer9
- Application Supplier NoteWB: 1:500-1:3000. IHC-P: 1:100-1:1000. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
- ApplicationsImmunoFluorescence, Western Blot, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
- CertificationResearch Use Only
- ClonalityPolyclonal
- Concentration1.31 mg/ml
- ConjugateUnconjugated
- Gene ID3643
- Target nameINSR
- Target descriptioninsulin receptor
- Target synonymsCD220; HHF5; insulin receptor; IR
- HostRabbit
- IsotypeIgG
- Protein IDP06213
- Protein NameInsulin receptor
- Scientific DescriptionAfter removal of the precursor signal peptide, the insulin receptor precursor is post-translationally cleaved into two chains (alpha and beta) that are covalently linked. Binding of insulin to the insulin receptor (INSR) stimulates glucose uptake. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq]
- ReactivityHuman, Mouse, Rat, Zebra Fish
- Storage Instruction-20°C or -80°C,2°C to 8°C
- UNSPSC12352203
References
- An inducible model of chronic hyperglycemia.Read more
- Oral administration of nano-tyrosol reversed the diabetes-induced liver damage in streptozotocin-induced diabetic rats.Read more
- Radix Rehmanniae Praeparata (Shu Dihuang) exerts neuroprotective effects on ICV-STZ-induced Alzheimers disease mice through modulation of INSR/IRS-1/AKT/GSK-3beta signaling pathway and intestinal microbiota.Read more
- Activation of AT2 receptors prevents diabetic complications in female db/db mice by NO-mediated mechanisms. Dominici FP et al., 2020 Oct, Br J PharmacolRead more
- Regulation of chitosan-mediated differentiation of human olfactory receptor neurons by insulin-like growth factor binding protein-2. Huang TW et al., 2019 Oct 1, Acta BiomaterRead more
- 3,3-Diindolylmethane Enhances Glucose Uptake Through Activation of Insulin Signaling in 3T3-L1 Adipocytes. Choi KM et al., 2018 Jul, Obesity (Silver Spring)Read more
- PTPRD silencing by DNA hypermethylation decreases insulin receptor signaling and leads to type 2 diabetes. Chen YT et al., 2015 May 30, OncotargetRead more