Anti-Histone H2B Antibody [SD20-63]

HUABIO

Anti-Histone H2B Antibody [SD20-63]

7

ImmunoFluorescence, ImmunoPrecipitation, Western Blot, ChIP Chromatin ImmunoPrecipitation, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin

WB,IF-Cell,IF-Tissue,IHC-P,IP,FC

Research Use Only

Monoclonal

SD20-63

1 mg/ml

Unconjugated

H2bc1

H2B clustered histone 1

Hist1h2ba, Th2b, histone, histone H2B type 1-A, histone 1, H2ba, histone H2B, testis, histone cluster 1 H2B family member a, histone cluster 1, H2ba, testis-specific histone 2b, testis-specific histone H2B

Rabbit

IgG

Histone H2B type 1-K

Eukaryotic histones are basic and water soluble nuclear proteins that form hetero-octameric nucleosome particles by wrapping 146 base pairs of DNA in a left-handed super-helical turn sequentially to form chromosomal fiber. Two molecules of each of the four core histones (H2A, H2B, H3, and H4) form the octamer; formed of two H2A-H2B dimers and two H3-H4 dimers, forming two nearly symmetrical halves by tertiary structure. Over 80% of nucleosomes contain the linker Histone H1, derived from an intronless gene, that interacts with linker DNA between nucleosomes and mediates compaction into higher order chromatin. Histones are subject to posttranslational modification by enzymes primarily on their N-terminal tails, but also in their globular domains. Such modifications include methylation, citrullination, acetylation, phosphorylation, sumoylation, ubiquitination and ADP-ribosylation.

Human, Mouse, Rat

Human,Mouse,Rat

-20°C,2°C to 8°C

41116161