Anti-Histone H3 Rabbit mAb

PTM BIO

Anti-Histone H3 Rabbit mAb

5

Western Blot, ImmunoHistoChemistry Paraffin

WB, IHC-P

Research Use Only

Monoclonal

JMMR-2423B

Unconjugated

Rabbit

IgG

Histone H3.1

Modulation of chromatin structure plays an important role in the regulation of transcription in eukaryotes. The nucleosome, made up of DNA wound around eight core histone proteins (two each of H2A, H2B, H3, and H4), is the primary building block of chromatin. Histone H3 is primarily acetylated at Lys9, 14, 18, 23, 27, and 56. Acetylation of H3 at Lys9 appears to have a dominant role in histone deposition and chromatin assembly in some organisms. Phosphorylatedrylation at Ser10, Ser28, and Thr11 of histone H3 is tightly correlated with chromosome condensation during both mitosis and meiosis.

Stable for 12 months from date of receipt/reconstitution.

Human, Mouse, Rat, Monkey

Protein A purified

Store at -20°C. Avoid freeze/thaw cycles.

12352203