Anti-HIV-1 gp120 [694-D]

Absolute Antibody

Anti-HIV-1 gp120 [694-D]

7

This antibody was demonstrated to be neutralizing against HIV (Buchbinder et al., 1992; pmid: 1466965). It can be used synergistically with other neutralizing HIV antibodies (such as 447-D). This clone inhibits the binding of gp120 to soluble recombinant CD4 (Buchbinder et al., 1992; pmid: 1466965). Consequently, this antibody is recommended for research on the develpment of successful treatment and prevention of HIV infection, as effective neutralizing antibodies are capable of depleting the viral load in patients exposed to the virus.

Functional Assay, ImmunoFluorescence, Western Blot, ELISA, Neutralisation/Blocking

Neutralizing; WB; ELISA; IF; functional assays

Research Use Only

Envelope glycoprotein gp160

This chimeric mouse antibody was made using the variable domain sequences of the original Human IgG1 format, for improved compatibility with existing reagents, assays and techniques.

-20°C,2°C to 8°C

12352203