Anti-HIV-1 GP120 [YZ23]

Absolute Antibody

Anti-HIV-1 GP120 [YZ23]

9

This antibody binds irreversibly with GP120 of the HIV-1 virus. This antibody shows specific binary reactivity for peptides containing amino acid residues 292-306 and 421- 433 of the gp120 protein.

This antibody is capable of irreversibly binding both HIV-1 GP120 and its covalently reactive analogue in an ELISA. (PMID: 12665517). This antibody neutralized the infection of peripheral blood mononuclear cells by a primary HIV-1 isolate belonging to clade C (strain ZA009) (PMID: 16838382). It is also capable of neutralizing genetically diverse HIV strains like 92RW008, PAVO, SF162, 92BR021, QHO692, 92BR020, 98BR004, Du172, Du422, 97ZA009 and 98TZ017 (PMID: 19726674).

ELISA, Neutralisation/Blocking

Research Use Only

Monoclonal

YZ23

env

Envelope surface glycoprotein gp160, precursor

Envelope surface glycoprotein gp160, precursor; HIV1gp8

Rabbit

IgG

Envelope glycoprotein gp160

This chimeric rabbit antibody was made using the variable domain sequences of the original Mouse IgG2a format, for improved compatibility with existing reagents, assays and techniques.

Virus

-20°C,2°C to 8°C

12352203