Anti-HLA-Cw6 [Cw6_4]

Absolute Antibody

Anti-HLA-Cw6 [Cw6_4]

7

This antibody binds human HLA-Cw6. This antigen-presenting major histocompatibility complex class I (MHCI) molecule has an important role in reproduction and antiviral immunity.

The binding specificity of the scFv antibody towards human HLA-Cw6, expressed on the cell surface was done using flow cytometry. This antibody was also used for the immunoprecipitation of Cw*0602-transfected LCL721.221 cells (WO2001014558).

Flow Cytometry, ImmunoPrecipitation

FC; IP

Research Use Only

Monoclonal

Cw6_4

HLA-C

major histocompatibility complex, class I, C

D6S204; HLA class I histocompatibility antigen, C alpha chain; HLAC; HLA-C antigen; HLA-JY3; HLC-C; human leukocyte antigen-C alpha chain; major histocompatibility antigen HLA-C; MHC; MHC class I antigen heavy chain HLA-C; PSORS1

Rabbit

IgG

HLA class I histocompatibility antigen, Cw-7 alpha chain

This full-length chimeric rabbit antibody was made using the variable domain sequences of the original Human scFv format for improved compatibility with existing reagents assays and techniques.

Human

Human

The original antibody was isolated from fully synthetic human combinatorial antibody library (HuCAL) by screening against a cell-bound human lymphocyte antigen HLA-Cw6. Cw6 stable cell line was generated by transfecting human lymphoblastoid LCL 721.221 HLA class I null cell line.

-20°C,2°C to 8°C

12352203