Anti-HLA DMB Antibody [JE58-74]
HA720038
ApplicationsFlow Cytometry, ImmunoFluorescence, Western Blot
Product group Antibodies
TargetHLA-DMB
Overview
- SupplierHUABIO
- Product NameAnti-HLA DMB Antibody [JE58-74]
- Delivery Days Customer2
- ApplicationsFlow Cytometry, ImmunoFluorescence, Western Blot
- CertificationResearch Use Only
- ClonalityMonoclonal
- Clone IDJE58-74
- Concentration1 mg/ml
- ConjugateUnconjugated
- Gene ID3109
- Target nameHLA-DMB
- Target descriptionmajor histocompatibility complex, class II, DM beta
- Target synonymsD6S221E, RING7, HLA class II histocompatibility antigen, DM beta chain, MHC class II HLA-DMB, MHC class II antigen DMB, MHC class II antigen HLA-DM beta chain, class II histocompatibility antigen, M beta chain, really interesting new gene 7 protein
- HostRabbit
- IsotypeIgG
- Protein IDP28068
- Protein NameHLA class II histocompatibility antigen, DM beta chain
- Scientific DescriptionHLA-DMB belongs to the HLA class II beta chain paralogues. This class II molecule is a heterodimer consisting of an alpha (DMA) and a beta (DMB) chain, both anchored in the membrane. It is located in intracellular vesicles. DM plays a central role in the peptide loading of MHC class II molecules by helping to release the CLIP (class II-associated invariant chain peptide) molecule from the peptide binding site. Class II molecules are expressed in antigen presenting cells (APC: B lymphocytes, dendritic cells, macrophages). The beta chain is approximately 26-28 kDa and its gene contains 6 exons. Exon one encodes the leader peptide, exons 2 and 3 encode the two extracellular domains, exon 4 encodes the transmembrane domain and exon 5 encodes the cytoplasmic tail.
- Storage Instruction-20°C,2°C to 8°C
- UNSPSC41116161