Anti-HLA-DPA1 Rabbit mAb

PTM BIO

Anti-HLA-DPA1 Rabbit mAb

5

ImmunoFluorescence, Western Blot, ImmunoCytoChemistry, ImmunoHistoChemistry Paraffin

WB, IHC-P, ICC/IF

Antibody

Research Use Only

Monoclonal

JRMR-234

Unconjugated

Rabbit

IgG

HLA class II histocompatibility antigen, DP alpha 1 chain

Binds peptides derived from antigens that access the endocytic route of antigen presenting cells (APC) and presents them on the cell surface for recognition by the CD4 T-cells. The peptide binding cleft accommodates peptides of 10-30 residues. The peptides presented by MHC class II molecules are generated mostly by degradation of proteins that access the endocytic route, where they are processed by lysosomal proteases and other hydrolases. Exogenous antigens that have been endocytosed by the APC are thus readily available for presentation via MHC II molecules, and for this reason this antigen presentation pathway is usually referred to as exogenous.

Stable for 12 months from date of receipt/reconstitution.

Human, Mouse

Protein A purified

Store at -20°C. Avoid freeze/thaw cycles.

12352203