Anti-HP1 gamma Mouse mAb

PTM BIO

Anti-HP1 gamma Mouse mAb

5

ImmunoFluorescence, Western Blot, ImmunoCytoChemistry, ImmunoHistoChemistry Paraffin

WB, IHC-P, ICC/IF

Research Use Only

Monoclonal

JMMR-1208

Unconjugated

Mouse

IgG

Chromobox protein homolog 3

HP1 gamma (HP1gamma) is a member of Heterochromatin protein 1 (HP1) family, which is involved in both gene silencing and higher order chromatin structure. All three HP1 family members (alfa, bèta, and gamma) are primarily associated with centromeric heterochromatin; however, HP1bèta and gamma also localize to euchromatic sites in the genome. HP1 proteins are approximately 25 kDa in size and contain a conserved amino-terminal chromodomain, followed by a variable hinge region and a conserved carboxy-terminal chromoshadow domain. The chromodomain facilitates binding to histone H3 Trimethylated at Lys9, a histone mark closely associated with centromeric heterochromatin.

Stable for 12 months from date of receipt/reconstitution.

Human, Mouse, Rat

Human, Mouse, Rat

Protein A purified

Store at -20°C. Avoid freeze/thaw cycles.

12352203