Anti-HspB3 [7B4]

Absolute Antibody

Anti-HspB3 [7B4]

7

The antibody is specific for HspB3. HspB3 is an inhibitor of actin polymerization and it promotes myogenesis by regulating the lamin B receptor.

The specificity of the original format of the antibody was confirmed by ELISA analysis (Hof et al., 2008; PMID: 18062792).

ELISA

ELISA

Research Use Only

Monoclonal

7B4

HSPB3

heat shock protein family B (small) member 3

DHMN2C; heat shock 17 kDa protein; heat shock 27kDa protein 3; heat shock protein beta-3; HMN2C; HSP 17; HSPL27; protein 3

Rabbit

IgG

Heat shock protein beta-3

This full-length chimeric rabbit antibody was made using the variable domain sequences of the original Chicken scFv format for improved compatibility with existing reagents assays and techniques.

Human

Human

The original antibody was generated by immunizing a barnevelder chicken with an antibody antigen cocktail comprising recombinant purified human antigens alfa-fodrin, hPop1, HspB3, Ro52, Rpp30, Rrp4 and Rrp42 in complete Freund's adjuvant. B cells that were harvested from the bone marrow and peripheral blood lymphocytes of immunized chickens was used to generate recombinant scFv phage display libraries. The specific clone was identified by panning the library against specific antigen.

-20°C,2°C to 8°C

12352203