Anti-Hu CD231 Purified

EXBIO

Anti-Hu CD231 Purified

7

Immunohistochemistry: Positive control: brain. Flow cytometry: Recommended dilution: 1-4 microg/ml

Flow Cytometry, ImmunoPrecipitation, Western Blot, ImmunoHistoChemistry

Research Use Only

B2D

1 mg/ml

IgG1

CD231 (TALLA-1, T-ALL-asociated antigen 1), also known as tetraspanin 7, is a 150 kDa (under reducing conditions 32-45 kDa) transmembrane glycoprotein of tetraspanin family, expressed in T-type acute lymphoblastic leukemia, neuroblastoma, and neuronal tissue. Mutations of CD231 gene are associated with X-linked mental retardation, Huntingtons chorea, and myotonic dystrophy. CD231 interacts with integrins and may have a role in the control of neurite outgrowth. Antibodies to CD231 are important for detection of T-ALL and are potential targets of its treatment.

Human

2°C to 8°C

12352203