Anti-Hu CD85d APC

EXBIO

Anti-Hu CD85d APC

7

Flow cytometry: The reagent is designed for analysis of human blood cells using 10 microl reagent / 100 microl of whole blood or 106 cells in a suspension. The content of a vial (1 ml) is sufficient for 100 tests.

Flow Cytometry

Research Use Only

42D1

APC (Allophycocyanin)

IgG2a

CD85d is a type I transmembrane glycoprotein of the ILT/LIR family, which contains three intracellular ITIMs. It is expressed on NK cells, monocytes, macrophages, and weakly granulocytes. CD85d binds classic HLA class I molecules, and non-classic HLA-G1, and is involved in the suppression of NK cell-mediated cytotoxicity. Interaction between CD85d and trophoblast-specific HLA-G1 probably contributes to maternal tolerance of the fetus by inhibiting maternal leukocytes. Antigen presenting cells expressing CD85d and CD85k appear to be crucial to the generation of CD8+ suppressor T cells and CD4+ regulatory T cells.

Human

2°C to 8°C

12352203