Anti-Hu CD96 APC

EXBIO

Anti-Hu CD96 APC

7

Flow cytometry: The reagent is designed for analysis of human blood cells using 10 microl reagent / 100 microl of whole blood or 106 cells in a suspension. The content of a vial (1 ml) is sufficient for 100 tests.

Flow Cytometry

Research Use Only

NK92.39

APC (Allophycocyanin)

IgG1

CD96 is a 160-240 kDa type I transmembrane glycoprotein with intracellular ITIM-like domain, however, without observed inhibitory function. This protein is involved in adhesive interactions of T and NK cells during the late phase of the immune response, and are expressed above all upon their activation. Strong interaction between CD96 and CD155 (poliovirus receptor) stimulates cytotoxicity of activated NK cells, which may play a role in NK cell recognition and killing of CD155-expressing tumor cells. CD96 is expressed on approximately 80% of T cell leukemias and 30% of acute myeloid leukemias and is being used for their immunophenotyping.

Human

2°C to 8°C

12352203